Ιδρυματικό Αποθετήριο
Πολυτεχνείο Κρήτης
Πολυτεχνείο Κρήτης
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| URI: | http://purl.tuc.gr/dl/dias/74724FF0-247B-4F5B-986F-E65BC0FD3BCA | ||
| Έτος | 2015 | ||
| Τύπος | Δημοσίευση σε Περιοδικό με Κριτές | ||
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| Βιβλιογραφική Αναφορά | K. C. Tsolis, E. S. Bei, I. Papathanasiou, F.Kostopoulou, V. Gkretsi, K.Kalantzaki, K. Malizos, M.Zervakis, A. Tsezou, A. Economou ,"Comparative proteomic analysis of hypertrophic chondrocytes in osteoarthritis,"Clinical prot.,vol. 12 ,no.1,pp. 1-16,2015.doi:10.1186/s12014-015-9085-6 https://doi.org/10.1186/s12014-015-9085-6 | ||
| Εμφανίζεται στις Συλλογές |
Osteoarthritis (OA) is a multi-factorial disease leading progressively to loss of articular cartilage and subsequently to loss of joint function. While hypertrophy of chondrocytes is a physiological process implicated in the longitudinal growth of long bones, hypertrophy-like alterations in chondrocytes play a major role in OA. We performed a quantitative proteomic analysis in osteoarthritic and normal chondrocytes followed by functional analyses to investigate proteome changes and molecular pathways involved in OA pathogenesis.
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