Institutional Repository
Technical University of Crete
Technical University of Crete
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| URI | http://purl.tuc.gr/dl/dias/391E8519-D54E-4D08-927B-18047B78DF9D | - |
| Identifier | https://doi.org/10.4236/jbise.2010.35070 | - |
| Language | en | - |
| Extent | 8 pages | en |
| Title | Diffusive modelling of glioma evolution: a review | en |
| Creator | Zervakis Michalis | en |
| Creator | Ζερβακης Μιχαλης | el |
| Creator | Sakkalis, Vangelis | en |
| Creator | Kostas Marias | en |
| Creator | Alexandros Roniotis | en |
| Content Summary | Gliomas, the most aggressive form of brain cancer, are known for their widespread invasion into the tis-sue near the tumor lesion. Exponential models, which have been widely used in other types of cancers, can-not be used for the simulation of tumor growth, due to the diffusive behavior of glioma. Diffusive models that have been proposed in the last two decades seem to better approximate the expansion of gliomas. This paper covers the history of glioma diffusive model-ling, starting from the simplified initial model in 90s and describing how this have been enriched to take into account heterogenous brain tissue, anisotropic migration of glioma cells and adjustable proliferation rates. Especially, adjustable proliferation rates are very important for modelling therapy plans and per-sonalising therapy to different patients | en |
| Type of Item | Peer-Reviewed Journal Publication | en |
| Type of Item | Δημοσίευση σε Περιοδικό με Κριτές | el |
| License | http://creativecommons.org/licenses/by/4.0/ | en |
| Date of Item | 2015-10-23 | - |
| Date of Publication | 2010 | - |
| Subject | Neuroscience | en |
| Bibliographic Citation | A. Roniotis, K.Marias, V. Sakkalis, M. Zervakis,"Diffusive modelling of glioma evolution: a review,"J. Biom. Science and Eng., vol.3,no.5,pp. 501-508 ,2010.doi:10.4236/jbise.2010.35070 | en |
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