Ιδρυματικό Αποθετήριο
Πολυτεχνείο Κρήτης
EN  |  EL

Αναζήτηση

Πλοήγηση

Ο Χώρος μου

Multi-platform data integration in microarray analysis

Zervakis Michail, Sanidas, Elias, Potamias, Georgios, 1953-, Kafetzopoulos Dimitrios , Tsiliki Georgia, Ioannou Marina

Απλή Εγγραφή


URIhttp://purl.tuc.gr/dl/dias/2FE6CD0E-0F52-4B21-85FF-E225ABD8412B-
Αναγνωριστικόhttps://doi.org/10.1109/TITB.2011.2158232-
Αναγνωριστικόhttps://ieeexplore.ieee.org/document/6083509-
Γλώσσαen-
Μέγεθος7 pagesen
ΤίτλοςMulti-platform data integration in microarray analysisen
ΔημιουργόςZervakis Michailen
ΔημιουργόςΖερβακης Μιχαηλel
ΔημιουργόςSanidas, Eliasen
ΔημιουργόςPotamias, Georgios, 1953-en
ΔημιουργόςKafetzopoulos Dimitrios en
ΔημιουργόςTsiliki Georgiaen
ΔημιουργόςIoannou Marinaen
ΕκδότηςInstitute of Electrical and Electronics Engineersen
ΠερίληψηAn increasing number of studies have profiled gene expressions in tumor specimens using distinct microarray plat forms and analysis techniques. One challenging task is to develop robust statistical models in order to integrate multi-platform findings. We compare some methodologies on the field with respect to estrogen receptor (ER) status, and focus on a unified-among platforms scale implemented by Shen et at. in 2004, which is based on a Bayesian mixture model. Under this scale, we study the ER intensity similarities between four breast cancer datasets derived from various platforms. We evaluate our results with an independent dataset in terms of ER sample classification, given the derived gene ER signatures of the integrated data. We found that integrated multi-platform gene signatures and fold-change variability similarities between different platform measurements can assist the statistical analysis of independent microarray datasets in terms of ER classification. en
ΤύποςPeer-Reviewed Journal Publicationen
ΤύποςΔημοσίευση σε Περιοδικό με Κριτέςel
Άδεια Χρήσηςhttp://creativecommons.org/licenses/by/4.0/en
Ημερομηνία2015-10-24-
Ημερομηνία Δημοσίευσης2011-
Θεματική ΚατηγορίαClinical laboratory techniciansen
Θεματική ΚατηγορίαMedical laboratory techniciansen
Θεματική Κατηγορίαmedical technologistsen
Θεματική Κατηγορίαclinical laboratory techniciansen
Θεματική Κατηγορίαmedical laboratory techniciansen
Βιβλιογραφική ΑναφοράG. Tsiliki, M. Zervakis, M. Ioannou, E. Sanidas, E. Stathopoulos and G. Potamias, "Multi-platform data integration in microarray analysis," IEEE Trans. Inf. Techn. Biom., vol. 15, no.6, pp. 806-812, Nov. 2011. doi: 10.1109/TITB.2011.2158232el

Υπηρεσίες

Στατιστικά