Institutional Repository
Technical University of Crete
Technical University of Crete
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| URI | http://purl.tuc.gr/dl/dias/74724FF0-247B-4F5B-986F-E65BC0FD3BCA | - |
| Identifier | https://doi.org/10.1186/s12014-015-9085-6 | - |
| Language | en | - |
| Extent | 16 pages | en |
| Title | Comparative proteomic analysis of hypertrophic chondrocytes in osteoarthritis | en |
| Creator | Zervakis Michalis | en |
| Creator | Ζερβακης Μιχαλης | el |
| Creator | Ioanna Papathanasiou | en |
| Creator | Vassiliki Gkretsi | en |
| Creator | Kalliopi Kalantzaki | en |
| Creator | Anastassios Economou | en |
| Creator | Konstantinos Malizos | en |
| Creator | Konstantinos C. Tsolis | en |
| Publisher | BioMed Central | en |
| Content Summary | Osteoarthritis (OA) is a multi-factorial disease leading progressively to loss of articular cartilage and subsequently to loss of joint function. While hypertrophy of chondrocytes is a physiological process implicated in the longitudinal growth of long bones, hypertrophy-like alterations in chondrocytes play a major role in OA. We performed a quantitative proteomic analysis in osteoarthritic and normal chondrocytes followed by functional analyses to investigate proteome changes and molecular pathways involved in OA pathogenesis. | en |
| Type of Item | Peer-Reviewed Journal Publication | en |
| Type of Item | Δημοσίευση σε Περιοδικό με Κριτές | el |
| License | http://creativecommons.org/licenses/by/4.0/ | en |
| Date of Item | 2015-10-25 | - |
| Date of Publication | 2015 | - |
| Subject | Basic medical sciences | en |
| Subject | Basic sciences, Medical | en |
| Subject | Biomedical sciences | en |
| Subject | Health sciences | en |
| Subject | Preclinical sciences | en |
| Subject | Sciences, Medical | en |
| Subject | medical sciences | en |
| Subject | basic medical sciences | en |
| Subject | basic sciences medical | en |
| Subject | biomedical sciences | en |
| Subject | health sciences | en |
| Subject | preclinical sciences | en |
| Subject | sciences medical | en |
| Bibliographic Citation | K. C. Tsolis, E. S. Bei, I. Papathanasiou, F.Kostopoulou, V. Gkretsi, K.Kalantzaki, K. Malizos, M.Zervakis, A. Tsezou, A. Economou ,"Comparative proteomic analysis of hypertrophic chondrocytes in osteoarthritis,"Clinical prot.,vol. 12 ,no.1,pp. 1-16,2015.doi:10.1186/s12014-015-9085-6 | en |
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