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Integrating microarray data and gene regulatory networks: survey and critical considerations

Zervakis Michail, Potamias, Georgios, Moustakis Vasilis, Koumakis, Leonidas

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URIhttp://purl.tuc.gr/dl/dias/38D31CE6-6BEE-4B7A-BFA9-6F719DAA55A5-
Identifierhttps://doi.org/10.1109/IWBE.2011.6079034-
Identifierhttps://ieeexplore.ieee.org/document/6079034/-
Languageen-
Extent4 pagesen
TitleIntegrating microarray data and gene regulatory networks: survey and critical considerationsen
CreatorZervakis Michailen
CreatorΖερβακης Μιχαηλel
CreatorPotamias, Georgiosen
CreatorMoustakis Vasilisen
CreatorΜουστακης Βασιληςel
CreatorKoumakis, Leonidasen
PublisherInstitute of Electrical and Electronics Engineersen
Content SummaryMicroarray gene expression and gene regulatory interactions are two of the most significant data sources in the areas of molecular biology and biotechnology. In this article we survey existing methods and tools supporting the integration of these two data sources. We start with gene regulatory network reconstruction methods focusing on the reconstruction using microarray experiments. Then we discuss methods and tools for gene expression data analysis based on gene regulatory network knowledge and we review algorithms and tools for gene regulatory networks selection using microarray data. Finally we introduce a new methodology for the identification of differentially expressed functional paths or sub-paths within a gene regulatory network using microarray data analysis.en
Type of ItemΠλήρης Δημοσίευση σε Συνέδριοel
Type of ItemConference Full Paperen
Licensehttp://creativecommons.org/licenses/by/4.0/en
Date of Item2015-10-25-
Date of Publication2011-
SubjectBasic medical sciencesen
SubjectBasic sciences, Medicalen
SubjectBiomedical sciencesen
SubjectHealth sciencesen
SubjectPreclinical sciencesen
SubjectSciences, Medicalen
Subjectmedical sciencesen
Subjectbasic medical sciencesen
Subjectbasic sciences medicalen
Subjectbiomedical sciencesen
Subjecthealth sciencesen
Subjectpreclinical sciencesen
Subjectsciences medicalen
SubjectGene expressionen
SubjectBioinformaticsen
SubjectData analysisen
SubjectBiological system modelingen
SubjectData miningen
SubjectCanceren
Bibliographic CitationL. Koumakis, G. Potamias, M. Zervakis and V. Moustakis ,"Integrating microarray data and gene regulatory networks: survey and critical considerations ,"in 10th International Workshop on Biomedical Engineering, 2011, pp. 1-4. doi: 10.1109/IWBE.2011.6079034en

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