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Evaluation of short- and long-term response to treatment in GIMEMA protocol for acute myeloid leukaemia

Zervakis Michail, Kounelakis M. G., Manikis G., Iacobelli, Silvia, Ardoino I., Boracchi P., Lisboa P.J.G.

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URIhttp://purl.tuc.gr/dl/dias/3CB4A03C-9D1E-4BB7-A8A2-3503C6B2AEEC-
Identifierhttps://doi.org/10.1504/IJBET.2010.032699-
Identifierhttps://www.inderscienceonline.com/doi/abs/10.1504/IJBET.2010.032699-
Languageen-
Extent20 pagesen
TitleEvaluation of short- and long-term response to treatment in GIMEMA protocol for acute myeloid leukaemiaen
CreatorZervakis Michailen
CreatorΖερβακης Μιχαηλel
CreatorKounelakis M. G.en
CreatorManikis G.en
CreatorIacobelli, Silviaen
CreatorArdoino I.en
CreatorBoracchi P.en
CreatorLisboa P.J.G.en
PublisherInderscienceen
Content SummaryAcute Myeloid Leukaemia (AML) is a haematologic malignancy. Despite of improvements in prognosis it is still a severe disease and only a minority of patients are cured. Recently, insights into specific cytogenetics and biological aberration involved in the leukaemogenesis process are the target of research. LAM-99P GIMEMA Protocol identifies treatment guidelines for AML in adults. A methodological approach is proposed, compounding different modelling techniques, to assess the prognostic relevance of clinical as well as biological markers with regard to clinical endpoint, such as the achievement of Complete Remission in the short-term and long-term survival taking into account competing risks.en
Type of ItemPeer-Reviewed Journal Publicationen
Type of ItemΔημοσίευση σε Περιοδικό με Κριτέςel
Licensehttp://creativecommons.org/licenses/by/4.0/en
Date of Item2015-10-25-
Date of Publication2010-
SubjectBasic medical sciencesen
SubjectBasic sciences, Medicalen
SubjectBiomedical sciencesen
SubjectHealth sciencesen
SubjectPreclinical sciencesen
SubjectSciences, Medicalen
Subjectmedical sciencesen
Subjectbasic medical sciencesen
Subjectbasic sciences medicalen
Subjectbiomedical sciencesen
Subjecthealth sciencesen
Subjectpreclinical sciencesen
Subjectsciences medicalen
SubjectAMLen
SubjectAcute Myeloid Leukaemiaen
SubjectSurvival analysisen
SubjectCompeting risksen
SubjectMultinomial logistic regressionen
SubjectSVMen
SubjectSupport Vector Machinesen
SubjectLong-term responseen
SubjectShort-term responseen
SubjectLeukaemia treatmenten
SubjectLAM-99P GIMEMA Protocolen
SubjectModellingen
SubjectClinical markersen
SubjectBiological markersen
Bibliographic CitationI. Ardoino, F. Ambrogi, S. Iacobelli, P. Boracchi, G. Manikis, M.G. Kounelakis, M. Zervakis, P.J.G. Lisboa, P. Fazi, M. Vignetti, E. M. Biganzoli and A. Starita, "Evaluation of short- and long-term response to treatment in GIMEMA protocol for acute myeloid leukaemia, "Intern. J. of Biomedical Eng. Techn., vol.3, no.3-4, pp.329-348. doi: 10.1504/IJBET.2010.032699en

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