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A general reconfigurable architecture for the BLAST algorithm

Sotiriadis Evripidis, Dollas Apostolos

Απλή Εγγραφή


URIhttp://purl.tuc.gr/dl/dias/3C1F1A68-33CD-49D7-A82E-99EA35371ADC-
Αναγνωριστικόhttp://link.springer.com/article/10.1007%2Fs11265-007-0069-2-
Αναγνωριστικόhttps://doi.org/10.1007/s11265-007-0069-2-
Γλώσσαen-
Μέγεθος20 pagesen
ΤίτλοςA general reconfigurable architecture for the BLAST algorithmen
ΔημιουργόςSotiriadis Evripidisen
ΔημιουργόςΣωτηριαδης Ευριπιδηςel
ΔημιουργόςDollas Apostolosen
ΔημιουργόςΔολλας Αποστολοςel
ΕκδότηςSpringer Verlagen
ΠερίληψηThe process of DNA sequence matching and database search is one of the major problems of the bioinformatics community. Major scientific efforts to address this problem have provided algorithms and software tools for molecular biologists since the early 1970s. At the algorithmic and software level BLAST is by far the most popular tool. It has been developed and continues to be maintained and distributed by the NCBI organization. The BLAST algorithm and software is computationally very intensive and as a result several computer vendors use it as a benchmark. On the other hand no systematic approach for hardware speedup of BLAST and its variants for different query and database size has been reported to date. In this paper we present our architecture that implements the BLAST algorithm for all of its major versions, and for any size of database and query. The system has been fully designed and partially implemented with reconfigurable logic. It consists of software and hardware parts and achieves a speedup of several times up to thousands of times vs general purpose computers.en
ΤύποςPeer-Reviewed Journal Publicationen
ΤύποςΔημοσίευση σε Περιοδικό με Κριτέςel
Άδεια Χρήσηςhttp://creativecommons.org/licenses/by/4.0/en
Ημερομηνία2015-11-02-
Ημερομηνία Δημοσίευσης2007-
Θεματική ΚατηγορίαFPGA BLASTen
Θεματική ΚατηγορίαReconfigurable BLAST architectureen
Θεματική ΚατηγορίαFPGA BLAST architecture en
Θεματική ΚατηγορίαBioinformatic hardwareen
Θεματική ΚατηγορίαBioinformatic FPGAen
Βιβλιογραφική ΑναφοράE. Sotiriades and A. Dollas, "A general reconfigurable architecture for the BLAST algorithm," J. VLSI Signal Process. Syst., vol. 48, no. 3, pp. 189-208, Sep. 2007. doi:10.1007/s11265-007-0069-2en

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