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Registration of fMRI on a 3D brain atlas for matching of functional activation compontments

Klados Georgios

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Year 2019
Type of Item Diploma Work
Bibliographic Citation Georgios Klados, "Registration of fMRI on a 3D brain atlas for matching of functional activation compontments", Diploma Work, School of Electrical and Computer Engineering, Technical University of Crete, Chania, Greece, 2019
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Many studies have focused on the association between different human brain regions in patients with brain lesion (stroke, traumatic brain injury, neurosurgery tissue removal) and their effects on cognitive, motor and sensitive functions. Nowadays, it is well established that the brain works as network and the symptoms in a person are a combination of the direct impact of the lesion in a single region and its connectivity with other healthy brain regions. The purpose of this work is to develop a user-friendly application that will attempt to find these physiological functions and psychological terms which are associated with given brain region (ROI) and the way that physiological terms affect the given brain region. In addition, it will attempt to find the brain regions that are activated together (co-activated) with the given brain region. Finally, it will provide two different ways of visualizing data for better observation and understanding. Thus, brain regions will be linked to functional terms and possible deficiencies in human operations will be estimated. The extracted information may provide information about the brain region that can help the doctors decide about a surgical incision. Finally, our application will warn the doctor about the cognitive deficits after Neurosurgery.

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