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Dissolved oxygen technologies as a novel strategy for non-healing wounds: a critical review

Venieri Danai, Ntentakis Dimitrios, Ntentaki Anastasia Maria, Kalomoiris Loukas, Kalogerakis Nikos, Delavogia Eleni, Arkadopoulos Nikolaos

Απλή Εγγραφή


URIhttp://purl.tuc.gr/dl/dias/D9F1618B-F9F1-4401-AF86-30508A12BEF0-
Αναγνωριστικόhttps://doi.org/10.1111/wrr.12972-
Αναγνωριστικόhttps://onlinelibrary.wiley.com/doi/10.1111/wrr.12972-
Γλώσσαen-
Μέγεθος18 pagesen
ΤίτλοςDissolved oxygen technologies as a novel strategy for non-healing wounds: a critical reviewen
ΔημιουργόςVenieri Danaien
ΔημιουργόςΒενιερη Δαναηel
ΔημιουργόςNtentakis Dimitriosen
ΔημιουργόςΝτεντακης Δημητριοςel
ΔημιουργόςNtentaki Anastasia Mariaen
ΔημιουργόςKalomoiris Loukasen
ΔημιουργόςKalogerakis Nikosen
ΔημιουργόςΚαλογερακης Νικοςel
ΔημιουργόςDelavogia Elenien
ΔημιουργόςArkadopoulos Nikolaosen
ΕκδότηςWileyen
ΠερίληψηNon-healing wounds are steadily becoming a global-health issue. Prolonged hypoxia propagates wound chronicity; yet, oxygenating treatments are considered inadequate to date. Dissolved oxygen (DO) in aqueous solutions introduces a novel approach to enhanced wound oxygenation, and is robustly evaluated for clinical applications. A systematic literature search was conducted, whereby experimental and clinical studies of DO technologies were categorized per engineering approach. Technical principles, methodology, endpoints and outcomes were analysed for both oxygenating and healing effects. Forty articles meeting our inclusion criteria were grouped as follows: DO solutions (17), oxygen (O2) dressings (9), O2 hydrogels (11) and O2 emulsions (3). All technologies improved wound oxygenation, each to a variable degree. They also achieved at least one statistically significant outcome related to wound healing, mainly in epithelialization, angiogenesis and collagen synthesis. Scarcity in clinical data and methodological variability precluded quantitative comparisons among the biotechnologies studied. DO technologies warrantee further evaluation for wound oxygenation in the clinical setting. Standardised methodologies and targeted research questions are pivotal to facilitate global integration in healthcare.en
ΤύποςΑνασκόπησηel
ΤύποςReviewen
Άδεια Χρήσηςhttp://creativecommons.org/licenses/by/4.0/en
Ημερομηνία2022-09-28-
Ημερομηνία Δημοσίευσης2021-
Θεματική ΚατηγορίαDissolved oxygenen
Θεματική ΚατηγορίαDissolved oxygen technologiesen
Θεματική ΚατηγορίαHealingen
Θεματική ΚατηγορίαOxygen solutionsen
Θεματική ΚατηγορίαWound oxygenen
Βιβλιογραφική ΑναφοράD. P. Ntentakis, A. M. Ntentaki, E. Delavogia, L. Kalomoiris, D. Venieri, N. Arkadopoulos, and N. Kalogerakis, “Dissolved oxygen technologies as a novel strategy for non‐healing wounds: a critical review,” Wound Rep. Reg., vol. 29, no. 6, pp. 1062–1079, Nov.-Dec. 2021, doi: 10.1111/wrr.12972.en

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