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Strengths and weaknesses of 1.5 T and 3T MRS data in brain glioma classification

Dī́mou, Giánnīs, 1944-, Zervakis Nikolaos, M.G. Kounelakis, I.I. Tsougos

Απλή Εγγραφή


URIhttp://purl.tuc.gr/dl/dias/E9AF6F71-5D0E-401C-8FC7-13ED5481A615-
Αναγνωριστικόhttps://doi.org/10.1109/TITB.2011.2131146-
Γλώσσαen-
Μέγεθος8 pagesen
ΤίτλοςStrengths and weaknesses of 1.5 T and 3T MRS data in brain glioma classificationen
ΔημιουργόςDī́mou, Giánnīs, 1944-en
ΔημιουργόςZervakis Nikolaosen
ΔημιουργόςΖερβακης Νικολαοςel
ΔημιουργόςM.G. Kounelakisen
ΔημιουργόςI.I. Tsougos en
ΕκδότηςInstitute of Electrical and Electronics Engineersen
ΠερίληψηAlthough magnetic resonance spectroscopy (MRS) methods of 1.5Tesla (T) and 3T have been widely applied during the last decade for noninvasive diagnostic purposes, only a few studies have been reported on the value of the information extracted in brain cancer discrimination. The purpose of this study is threefold. First, to show that the diagnostic value of the information extracted from two different MRS scanners of 1.5T and 3T is significantly influenced in terms of brain gliomas discrimination. Second, to statistically evaluate the discriminative potential of publicly known metabolic ratio markers, obtained from these two types of scanners in classifying low-, intermediate-, and high-grade gliomas. Finally, to examine the diagnostic value of new metabolic ratios in the discrimination of complex glioma cases where the diagnosis is both challenging and critical. Our analysis has shown that although the information extracted from 3T MRS scanner is expected to provide better brain gliomas discrimination; some factors like the features selected, the pulse-sequence parameters, and the spectroscopic data acquisition methods can influence the discrimination efficiency. Finally, it is shown that apart from the bibliographical known, new metabolic ratio features such as N-acetyl aspartate/S, Choline/S, Creatine/S , and myo-Inositol/S play significant role in gliomas grade discrimination.en
ΤύποςPeer-Reviewed Journal Publicationen
ΤύποςΔημοσίευση σε Περιοδικό με Κριτέςel
Άδεια Χρήσηςhttp://creativecommons.org/licenses/by/4.0/en
Ημερομηνία2015-10-24-
Ημερομηνία Δημοσίευσης2011-
Θεματική ΚατηγορίαProjects, Physicsen
Θεματική Κατηγορίαphysics projectsen
Θεματική Κατηγορίαprojects physicsen
Θεματική ΚατηγορίαBiomedicineen
Βιβλιογραφική ΑναφοράM.G. Kounelakis, I.N. Dimou, M.E. Zervakis, E. Tsolaki, E. Kousi, E. Kapsalaki,"Strengths and weaknesses of 1.5 T and 3T MRS data in brain glioma classification,"IEEE Trans. on Inf. Technology in Biom.,vol. 15,no.4,pp.647 - 654,2011.doi:10.1109/TITB.2011.2131146en

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