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In silico modeling and global optimization of dynamic bio-optical processes for probing, in vivo, biological features of neoplasia

Balas Costas, Papoutsoglou Georgios, Stamatiadou M.

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URIhttp://purl.tuc.gr/dl/dias/AC0EB294-A074-48E3-9FD4-0524AEB1B0D8-
Αναγνωριστικόhttps://doi.org/10.1109/iCBEB.2012.474-
Γλώσσαen-
ΤίτλοςIn silico modeling and global optimization of dynamic bio-optical processes for probing, in vivo, biological features of neoplasiaen
ΔημιουργόςBalas Costasen
ΔημιουργόςΜπαλας Κωσταςel
ΔημιουργόςPapoutsoglou Georgiosen
ΔημιουργόςΠαπουτσογλου Γεωργιοςel
ΔημιουργόςStamatiadou M.en
ΕκδότηςInstitute of Electrical and Electronics Engineersen
ΠερίληψηWe present the first in silico simulation of biomarker uptake kinetics and of the associated dynamic optical signals, measured in vivo in neoplastic epithelial tissue. We introduce a new, non-invasive method for estimating and mapping of both structural and functional, neoplasia-correlated parameters. The method relies on model-based fitting of dynamic optical signals, measured in vivo, and on solving the inverse problem with the aid of global sensitivity analysis and global optimization approaches.en
ΤύποςPeer-Reviewed Journal Publicationen
ΤύποςΔημοσίευση σε Περιοδικό με Κριτέςel
Άδεια Χρήσηςhttp://creativecommons.org/licenses/by/4.0/en
Ημερομηνία2015-10-19-
Ημερομηνία Δημοσίευσης2012-
Βιβλιογραφική ΑναφοράG. Papoutsoglou, M. Stamatiadou, C. Balas "In silico modeling and global optimization of dynamic bio-optical processes for probing, in vivo, biological features of neoplasia" IEEE-iCBCB 2012, Macau, China May 28-30, 2012,DOI:10.1109/iCBEB.2012.474en

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