Institutional Repository
Technical University of Crete
Technical University of Crete
EN
|
EL
| URI: | http://purl.tuc.gr/dl/dias/74724FF0-247B-4F5B-986F-E65BC0FD3BCA | ||
| Year | 2015 | ||
| Type of Item | Peer-Reviewed Journal Publication | ||
| License |
|
||
| Bibliographic Citation | K. C. Tsolis, E. S. Bei, I. Papathanasiou, F.Kostopoulou, V. Gkretsi, K.Kalantzaki, K. Malizos, M.Zervakis, A. Tsezou, A. Economou ,"Comparative proteomic analysis of hypertrophic chondrocytes in osteoarthritis,"Clinical prot.,vol. 12 ,no.1,pp. 1-16,2015.doi:10.1186/s12014-015-9085-6 https://doi.org/10.1186/s12014-015-9085-6 | ||
| Appears in Collections |
Osteoarthritis (OA) is a multi-factorial disease leading progressively to loss of articular cartilage and subsequently to loss of joint function. While hypertrophy of chondrocytes is a physiological process implicated in the longitudinal growth of long bones, hypertrophy-like alterations in chondrocytes play a major role in OA. We performed a quantitative proteomic analysis in osteoarthritic and normal chondrocytes followed by functional analyses to investigate proteome changes and molecular pathways involved in OA pathogenesis.
Copyright © DIAS 2013
