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Study of the stress-strain state for patient specific descending aortic aneurysms wall and their repair endograft

Mavrantzas Christos

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Summary

This thesis was prepared at the Laboratory of Biofluid Engineering & Biomedical Technology of the National Technical University of Athens, within the framework of the Master's Program in Product Design and Manufacturing of the School of Production Engineering and Management of the Technical University of Crete. The aim of this work is to study the stress-strain state and strength of the wall of patient specific descending thoracic aortic aneurysms as well as the repair endograft, in geometries resulting from the reconstruction of tomographic data with the reverse engineering method, in order to predict the blood flow and the effect of the walls of the descending thoracic aorta during a cardiac cycle. The anonymized medical records were provided by the Vascular Surgery Clinic of the University Hospital of Rio, Department of Medicine, School of Health Sciences of the University of Patras, after approval by the Ethics and Research Ethics Committee. The computational study is carried out with a two-fold approach, on the one hand with the Finite Elements Analysis (FEA) of the geometry as a deformable solid body describing the intensive state of the wall under the influence of the developing pressure inside the aorta and on the other hand through Computational Fluid Dynamics analysis (CFD), in the relevant blood control volumes. This approach uses data on the patients' circulatory system function, from a range of values found in the literature. The geometries, as well as the bibliographic data used, refer exclusively to the human body. The capabilities of suitable free software are used, such as FEBio (Finite Elements for Biomechanics) for finite element analysis, which is specially designed for applications in biomechanics, SimVascular through which the meshing is done and then the blood flow, the developing pressures are predicted and shear stresses in the walls of the descending aorta by solving the Navier-Stokes equations. Finally, the visualization of the results is done using the ParaView software.

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